Laboratory
laboratory
Laboratory of Fear Learning
http://www.md.rcm.upr.edu/quirk/Home.html
Website(s)
has URL
has_url
"Our lab studies the mechanisms of emotional regulation using extinction of conditioned fear. Much of what is known about extinction comes from animal models using Pavlovian fear conditioning. We found that a subregion of the prefrontal cortex, the infralimbic cortex (IL), is necessary for extinction (fear inhibition). Moreover, we found that another mPFC subregion, the prelimbic cortex (PL), is necessary for fear expression. We suggest that IL inhibits fear by inhibiting amygdala output, whereas PL drives fear by increasing amygdala output. In addition to our rat studies, we are now studying fear in humans, with the goal of developing new treatments for anxiety disorders."
Resource Description
resource_description
Contact
has contact
has_contact
Sotres, Francisco
PI
has PI
has_PI
Quirk, Gregory, Ph.D.
2010-09-11T07:21:40.568-05:00
emiranda (Edgar Miranda)
2011-11-01T13:53:03.679-05:00
workflow state
Published
tjohnson
nvasilevsky
etl
Agent
agent
agent
agent
Organization
organization
organization
organization
material_entity
independent_continuant
continuant
entity