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Effect of Low versus Moderate-intensity Endurance Exercise on Physical Functioning among Breast Cancer Survivors

eagle-i ID

http://upr.eagle-i.net/i/00000166-875e-6029-a49b-1f0d80000000

Resource Type

  1. Quantitative human study

Properties

  1. ClinicalTrials.gov url
    https://clinicaltrials.gov/ct2/show/NCT02982564
  2. Related grant number
    1SC3GM116684-01
  3. Additional Topic(s)
    Breast cancer
  4. Resource Description
    Improvements in early diagnosis and treatment for breast cancer in women have resulted in increased survivorship. An unintended consequence of increased survival, however, is that more women are living with the negative sequelae associated with cancer treatment, including decreased physical function. Exercise has been beneficial in arresting these sequelae, but adherence to exercise guidelines continues to be a challenge. As most breast cancer survivors are middle-aged and older, an alternative to enhance exercise engagement and adherence might be providing a low intensity exercise program. The overall purpose of this study is to assess the impact of a low intensity versus moderate intensity endurance exercise program on physical functioning on breast cancer survivors. It is hypothesized that participants of the low intensity exercise program will demonstrate similar physical functioning as participants in the moderate intensity exercise program. The Theory of Planned Behavior will serve as framework for the intervention. A convenience sample of 142 women, residents of Puerto Rico, age 50 or older, with a diagnosis of breast cancer, stage 0 thru III, who have received surgical treatment for breast cancer, with or without adjuvant therapy, will be randomly assigned to a low intensity or moderate intensity endurance intervention. Both interventions will be home-based, have a duration of 6 months, and be provided by physical therapists. An evaluator blinded to group assignment will assess participants at baseline and at completion of the intervention. Primary outcome measures will consist of physical functioning, and health-related quality of life.
  5. PI
    Mulero-Portela, Ana Leticia
  6. Topic
    disease of cellular proliferation
  7. Study Population
    Women who are breast cancer survivors, age 50 or over.
  8. Funded by
    National Institutes of Health
  9. Performed by
    Mulero-Portela, Ana Leticia Lab
 
RDFRDF
 
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The eagle-i Consortium is supported by NIH Grant #5U24RR029825-02 / Copyright 2016