Joshua Rosenthal Laboratory

People:

• PI: Rosenthal, Joshua, Ph.D.
  

Member: Soto, Sonia

Resources:

Instruments

• Axon Axopatch 200B Capacitor feedback patch clamp amplifier ( Patch clamp amplifier )
  

  "Widely accepted as the gold-standard for ultra low-noise patch clamp recordings, the Axopatch™ 200B Capacitor Feedback Patch Clamp Amplifier is the benchmark for single-channel recordings and other applications that require an excellent signal-to-noise ratio. By introducing active cooling of components in the headstage to well below 0°C, the open-circuit noise in patch mode has been reduced to unprecedented levels, as low as <15 fA (RMS) at 0.1 - 1 kHz. This translates into significantly lower noise during patch clamp recordings. A headstage that can be switched to resistive mode ensures superb performance in whole-cell recordings, too."

• Axon GeneClamp 500B amplifier ( Patch clamp amplifier )
  

  GeneClamp 500B is an electrophysiology amplifier.

• Barnstead International Max Q400 Incubator shaker ( Incubator shaker )
  

• Beckman Coulter J2-21 centrifuge ( Centrifuge )
  

• Labconco Chemical fume hood ( Chemical fume hood )
  

• MJ Research PTC-200 PCR machine ( PCR instrument )
  

• Nikon Eclipse E200 microscope ( Microscope )
  

• Nikon Instruments Eclipse TE2000-S Inverted microscope ( Inverted microscope )
  

• Nikon SMZ1000 microscope ( Microscope )
  

• Nikon SMZ645 microscope ( Microscope )
  

  Lab has two of these instruments.

• Olympus SZ40 microscope ( Microscope )
  

• Oocyte clamp ( Oocyte clamp )
  

• Oscilloscope ( Oscilloscope )
  

• PZMII microscope ( Microscope )
  

• Refricentro Cold room ( Cold room )
  

• Sutter P97 Micropipette puller ( Micropipette puller )
  

• Wescor Vapro 5520 osmometer ( Osmometer )
  

Web Links:

• http://www.neuro.upr.edu/faculty/rosenthal/rosenthal.html