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Walmor C. DeMello Laboratory

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Resources:

Instruments

  • Axon Axopatch 1D amplifier ( Analog-to-digital converter )

    The Axopath 1D features a lag control to provide stability and maintain current recording bandwidth. The Axopath ID also has a resistor-feedback technology for whole-cell, single-channel recording.

  • Axon Axopatch 200B Capacitor feedback patch clamp amplifier ( Analog-to-digital converter )

    "Widely accepted as the gold-standard for ultra low-noise patch clamp recordings, the Axopatch™ 200B Capacitor Feedback Patch Clamp Amplifier is the benchmark for single-channel recordings and other applications that require an excellent signal-to-noise ratio. By introducing active cooling of components in the headstage to well below 0°C, the open-circuit noise in patch mode has been reduced to unprecedented levels, as low as <15 fA (RMS) at 0.1 - 1 kHz. This translates into significantly lower noise during patch clamp recordings. A headstage that can be switched to resistive mode ensures superb performance in whole-cell recordings, too."

  • Axon Axopatch 200B Capacitor feedback patch clamp amplifier ( Patch clamp amplifier )

    "Widely accepted as the gold-standard for ultra low-noise patch clamp recordings, the Axopatch™ 200B Capacitor Feedback Patch Clamp Amplifier is the benchmark for single-channel recordings and other applications that require an excellent signal-to-noise ratio. By introducing active cooling of components in the headstage to well below 0°C, the open-circuit noise in patch mode has been reduced to unprecedented levels, as low as <15 fA (RMS) at 0.1 - 1 kHz. This translates into significantly lower noise during patch clamp recordings. A headstage that can be switched to resistive mode ensures superb performance in whole-cell recordings, too."

  • Axon Axopatch 200B Capacitor feedback patch clamp amplifier ( Patch clamp amplifier )

    "Widely accepted as the gold-standard for ultra low-noise patch clamp recordings, the Axopatch™ 200B Capacitor Feedback Patch Clamp Amplifier is the benchmark for single-channel recordings and other applications that require an excellent signal-to-noise ratio. By introducing active cooling of components in the headstage to well below 0°C, the open-circuit noise in patch mode has been reduced to unprecedented levels, as low as <15 fA (RMS) at 0.1 - 1 kHz. This translates into significantly lower noise during patch clamp recordings. A headstage that can be switched to resistive mode ensures superb performance in whole-cell recordings, too."

  • Axon Axopatch 200B Capacitor feedback patch clamp amplifier ( Patch clamp amplifier )

    Lab contains 2 of these instruments.

    "Widely accepted as the gold-standard for ultra low-noise patch clamp recordings, the Axopatch™ 200B Capacitor Feedback Patch Clamp Amplifier is the benchmark for single-channel recordings and other applications that require an excellent signal-to-noise ratio. By introducing active cooling of components in the headstage to well below 0°C, the open-circuit noise in patch mode has been reduced to unprecedented levels, as low as <15 fA (RMS) at 0.1 - 1 kHz. This translates into significantly lower noise during patch clamp recordings. A headstage that can be switched to resistive mode ensures superb performance in whole-cell recordings, too."

  • Axon Digital data analyzer ( Analog-to-digital converter )

    "The Digidata 1322A is a high-resolution, low-noise digitizer intended for precision scientific applications. The Digidata 1322A digitizes at an aggregate speed of 500 kHz. It provides sixteen multiplexed, 16-bit analog inputs and two non-multiplexed, 16-bit analog outputs. There are sixteen digital input lines and sixteen digital output lines, as well as Tag and Start digital inputs."

  • Axon GeneClamp 500B amplifier ( Patch clamp amplifier )

    GeneClamp 500B is an electrophysiology amplifier.

  • Axon Multiclamp 700B microelectrode amplifier ( Analog-to-digital converter )

    "The Multiclamp™ 700B Microelectrode Amplifier combines leading edge electronics design and a wealth of features and functions with an intuitive user interface that simplifies the creation of complex protocols. The applications for this amplifier comprise a wide variety of intracellular or extracellular recordings in electrophysiology, including:
    *Patch clamp (whole-cell, macro-patch, or excised patch)
    *High-speed current clamp (sharp-electrode or field potentials)
    *Voltammetry/amperometry
    *Ion-selective measurements
    *Bilayer recordings."

  • Dagan 8900 patch clamp amplifier ( Patch clamp amplifier )

    Lab contains two of this resource.

  • Dagan BVC-700 amplifier ( Patch clamp amplifier )

  • Leica cryostat ( Cryostat )

  • Molecular Devices, Inc. SpectraMax 190 absorbance microplate reader ( Microplate reader )

    "The patented multichannel optical design of the SpectraMax® 190 Absorbance Microplate Reader mimics a dual beam spectrophotometer, measures each sample in the plate directly, and eliminates measurement error due to variations in light output between optical fibers on other instruments for more reliable data reporting. The eight-channel system delivers both high precision and speed when reading 96-well microplates for endpoint measurements, kinetic assays, and spectral scans."

  • Stimulator ( Stimulator )

    Lab contains two copies of this resource.

  • Tektronix 5111A dual beam oscilloscope ( Oscilloscope )

    Connected to a four channel amplifier with 5B10N time base amplifier.

  • Tektronix oscilloscope ( Oscilloscope )

Software

  • MetaMorph ( Software )

    "MetaMorph Microscopy Automation & Image Analysis Software is the industry standard for automated microscope acquisition, device control, and image analysis, bringing microscopists greater understanding of cell morphology, function, and behavior."


Last updated: 2011-04-20T10:45:07.206-05:00

Copyright © 2016 by the President and Fellows of Harvard College
The eagle-i Consortium is supported by NIH Grant #5U24RR029825-02 / Copyright 2016